One seemingly innocuous phrase may have helped jump start the modern-day opioid abuse epidemic. The statement, used for years in marketing materials for the opiate painkiller OxyContin, implied that the drug was less likely than other similar medications to result in addiction. Specifically, the patient insert included with the drug from the time of its launch in 1996 (until the FDA required revamping in 2001) indicated that:
The FDA has a difficult balance to strike between adequate testing and pressure to get new drugs on the market quickly. This pressure can come from several sources, but especially from the manufacturers who stand to reap huge profits if the medications are approved and from its often well-connected shareholders who stand to benefit from the manufacturers' stock appreciation. As a consequence, and with limited resources, the FDA relies heavily upon information provided by the manufacturers themselves. Some FDA studies may be done with small groups, which can make it difficult to identify some side effects until the drugs are in wider usage.
Tennessee residents who rely on EpiPens to help them deal with sudden life-threatening allergic reactions should be aware that Mylan, the pharmaceutical company that distributes the device, has issued a recall. It affects certain lots of EpiPens and the children's version EpiPen Jr. that were sold in seven countries, including the United States.
Johnson & Johnson is currently the defendant in over 100,000 lawsuits, and many of them involve defective drugs and medical devices. People in Tennessee hurt by these products might have to be patient because the company appears to willing to fight claims for damages in court whenever feasible.
Many Tennessee residents have used a prescription medication known as Paxil, which is the brand name for the antidepressant drug paroxetine. However, the drug is known to cause several harmful side effects that consumers should be aware of.
Tennessee readers who have used the blood thinner Xarelto should be aware that the drug is known to cause harmful side effects. The medication carries a black box warning, which is the strongest type of warning issued by the U.S. Food and Drug Administration.
Tennessee residents who use Yaz for birth control or to treat moderate acne may be interested to learn that a number of side effects have been documented. As a result, the Food and Drug Administration has issued warnings and thousands of lawsuits against the company have been filed.
Xarelto is a blood thinner that has been prescribed to help reduce people's risk of developing blood clots, but it may be a dangerous drug due to unexpected side effects. Tennessee residents who underwent hip or knee replacement surgeries may have been given this drug to prevent deep vein thrombosis and pulmonary embolism. A pulmonary embolism is when a vein in the lungs becomes blocked due to a blood clot. Deep vein thrombosis is when blood clots form deep in the veins. Along with being prescribed for people who undergo hip and knee surgeries, the FDA also approved Xarelto for individuals with certain heart conditions to prevent blood clots.